NiggBernier2016

Reference

Nigg, M., Bernier, L. (2016) From yeast to hypha: defining transcriptomic signatures of the morphological switch in the dimorphic fungal pathogen Ophiostoma novo-ulmi. BMC Genomics, 17(1):920. (URL )

Abstract

Yeast-to-hypha transition is a major morphological change in fungi. Molecular regulators and pathways that are involved in this process have been extensively studied in model species, including Saccharomyces cerevisiae. The Mitogen-Actived Protein Kinase (MAPK) cascade, for example, is known to be involved in the yeast-to-pseudohypha switch. Yet the conservation of mechanisms regulating such morphological changes in non-model fungi is still poorly understood. Here, we investigate cell remodeling and transcriptomic modifications that occur during this morphological switch in the highly aggressive ascomycete fungus Ophiostoma novo-ulmi, the causal agent of Dutch elm disease.

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@ARTICLE { NiggBernier2016,
    AUTHOR = { Nigg, M. and Bernier, L. },
    TITLE = { From yeast to hypha: defining transcriptomic signatures of the morphological switch in the dimorphic fungal pathogen Ophiostoma novo-ulmi },
    JOURNAL = { BMC Genomics },
    YEAR = { 2016 },
    VOLUME = { 17 },
    PAGES = { 920 },
    NUMBER = { 1 },
    ABSTRACT = { Yeast-to-hypha transition is a major morphological change in fungi. Molecular regulators and pathways that are involved in this process have been extensively studied in model species, including Saccharomyces cerevisiae. The Mitogen-Actived Protein Kinase (MAPK) cascade, for example, is known to be involved in the yeast-to-pseudohypha switch. Yet the conservation of mechanisms regulating such morphological changes in non-model fungi is still poorly understood. Here, we investigate cell remodeling and transcriptomic modifications that occur during this morphological switch in the highly aggressive ascomycete fungus Ophiostoma novo-ulmi, the causal agent of Dutch elm disease. },
    DOI = { 10.1186/s12864-016-3251-8 },
    ISSN = { 1471-2164 },
    URL = { http://dx.doi.org/10.1186/s12864-016-3251-8 },
}

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